Saturated hydrocarbons
Cayman Chemical 12-oxo StearIc AcId 25mg
A metabolite of ricinoleic acid; has been found in cow and goat milk; dietary administration induces encephalomalacia in chicks fed a vitamin E-deficient diet
Medchemexpress LLC I-287 | 2014368-93-3 | 99.4% | 565.04 | 50 MG
I-287 is an orally active, selective PAR2 inhibitor that functions as a negative allosteric regulator of Gαq and Gα12/13 activity and their downstream effectors. It has been shown to reduce Complete Freund's adjuvant (CFA)-induced inflammation in mice and is suitable for inflammation/immunology research.
- Selectively targets Gαq and Gα12/13 signaling
- Inhibits PAR2-mediated activation of proteins without impacting βarrestin2 recruitment or receptor internalization
- Inhibits PAR2-mediated ERK1/2 activation in HEK293 cells
- Inhibits PAR2-induced secretion of IL-8 cytokine in HCT-116 and A549 cells
- Reduces inflammation in C57BL/6J mice
Medchemexpress LLC I-287 | 2014368-93-3 | 99.4% | 565.04 | 5 MG
I-287 is an orally active, selective PAR2 inhibitor that acts as a negative allosteric regulator on Gαq and Gα12/13 activity and their downstream effectors. It has been shown to reduce Complete Freund's adjuvant (CFA)-induced inflammation in mice and can be utilized for inflammation/immunology research.
- Inhibits PAR2-mediated activation of Gαq and Gα12/13.
- No effect on PAR2-mediated recruitment of βarrestin2 or receptor internalization.
- Inhibits PAR2-mediated ERK1/2 activation in HEK293 cells.
- Inhibits PAR2-induced secretion of IL-8 cytokine in HCT-116 and A549 cells.
- Reduces CFA-induced inflammation in C57BL/6J mice.
Medchemexpress LLC Octadecane-1-thiol-d37 | 668433-57-6 | 98.1% | 323.79 | 25 MG
Octadecane-1-thiol-d37 is the deuterium labeled Octadecane-1-thiol.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC 1-Octanesulfonic acid, sodium salt (1:1) | 5324-84-5 | 97.0% | 216.27 | 25 G
Sodium octane-1-sulfonate is an ion-pairing agent that can be used as a buffer in biochemical research and HPLC. It is for research use only.
- High purity: 99.92%
- Application: Used as an ion-pairing agent
- Functionality: Acts as a buffer
- Research utility: Suitable for biochemical research and HPLC applications
Selleck Chemical LLC MD-224
MD-224 is a highly potent and effective degrader of the Human murine double minute 2 (MDM2) protein the main cellular inhibitor of the tumor suppressor p53 It strongly inhibits cell growth in leukemia cell lines with wild-type p53 and induces complete and lasting tumor regression in the RS4 11 xenograft tumor model
Medchemexpress LLC MD-224 10mM | 10MM 1ML
MD-224 is a first-in-class and highly potent small-molecule human murine double minute 2 (MDM2) degrader based on the proteolysistargeting chimera (PROTAC) concept MD-224 consists of ligands for Cereblon and MDM2 MD-224 induces rapid degradation of MDM2 at concentrations 1 nM in human leukemia cells and achieves an IC50 value of 1 5 nM in inhibition of growth of RS4 11 cells MD-224 has the potential to be a new class of anticancer agent[1] MD-224 is a click chemistry reagent it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
Medchemexpress LLC 2-Methylcyclopentane-1,3-dione | 765-69-5 | MFCD00001406 | 100.0% | 112.13 | 100 G
2-Methylcyclopentane-1,3-dione is a key intermediate for the total synthesis of steroids. It is intended for research use only and not for sale to patients.
- Key intermediate for total synthesis of steroids
- For research use only
- Molecular weight: 112.13
- Purity: 99.96%
- CAS number: 765-69-5
- Appearance: Solid
- Color: White to light yellow
eMolecules Diethyl cyclopentane-1,1-dicarboxylate | 4167-77-5 | MFCD00219321 | 5g
Ambeed | Diethyl cyclopentane-1,1-dicarboxylate | 5g | 525193777 | A350634 | | 4167-77-5 | MFCD00219321 | 214.261 | C11H18O4
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eMolecules 1-Aminomethyl-cyclopentanecarboxylic acid hydrochloride | 1185298-24-1 | MFCD09864392 | 1g
Oakwood Chemical | 1-Aminomethyl-cyclopentanecarboxylic acid hydrochloride | 1g | 537705143 | 095260 | | 1185298-24-1 | MFCD09864392 | 179.640 | C7H14ClNO2
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Sigma Aldrich Fine Chemicals Biosciences 224-Trimethylpentane Reage
methyl 224-Trimethylpentane Reage
Medchemexpress LLC I-287 | 2014368-93-3 | 99.4% | 565.04 | 100 MG
I-287 | 2014368-93-3 | 99.4% | 565.04 | 100 MG
TARGETMOL CHEMICALS INC 9-hydroxy Stearic Acid 5MG
Also available in 1 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. 9-hydroxy Stearic Acid is a hydroxy fatty acid that is the active metabolite of 9-PAHSA. 9-hydroxy Stearic Acid is formed from 9-PAHSA through carboxyl ester lipase in the liver and pancreas. The 9-hydroxy Stearic Acid (5 uM) was stearic acid, which inhibited the expression of histone deacetylase 1 (HDAC1) in the lysate of HT-29 colon cancer cells. 3. When the concentration was 100 uM.1, the proliferation of HT-29 cells was inhibited and cell cycle arrest was induced in G0/ g1 phase. Purity 99.7%
Medchemexpress LLC Dynole 2-24 | 1416313-72-8 | 99.07% | C24H41N3 | 50 MG
Dynole 2-24 is an indole-based dynamin GTPase inhibitor. It is nontoxic and demonstrates increased potency against dynamin I and II both in vitro and within cells. This compound also exhibits selective inhibition of dynamin I and is an active in-cell inhibitor of clathrin-mediated endocytosis.
- Indole-based dynamin GTPase inhibitor.
- Has an IC50 of 0.56 μM for dynamin I.
- Nontoxic.
- Shows increased potency against dynamin I and II in vitro and in cells (IC₅₀(CME)=1.9 μM).
- Displays 4.4-fold selectivity for dynamin I.
- Functions as an active in-cell inhibitor of clathrin-mediated endocytosis.
Abcam 1,2-Distearoyl-sn-glycero-3-phosphorylglycerol sodium salt (DSPG), Phosphorylglycerol, 100MG
MW 801.1 Da, Purity >98%. Phosphorylglycerol acylated with stearic acid. Enhances respiratory mucus clearance in cystic fibrosis. For use in phospholipid studies and biological systems. See similar compounds
The product is subject to the following: Abcam Restricted Use Statement